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There are well recognized and utilized tools, diagnostic blood tests and diagnostic imaging options, that could help assess your risk of having advanced liver disease. Check them out below, and discuss your options with your Physician.
The Fibrosis-4 score helps to estimate the amount of scarring in the liver based on several laboratory tests.
The NAFLD Fibrosis score estimates the amount of scarring in the liver based on several laboratory tests.
"LIVERFASt™ is a blood based diagnostic test that combines 10 biomarkers and algorithm technology to determine the fibrosis, activity and steatosis stages of the liver."
Biomarkers included: Alpha-2-Macroglobulin, Haptoglobin, Apolipoprotein A1, Total Bilirubin, GGT, ALT (P5P), AST (P5P), Fasting Glucose, Triglyceride, and Total Cholesterol."
"A proprietary technology that underlies a novel, blood-based molecular biomarker test to rule in and/or rule out at-risk NASH (NAS ≥ 4 and F ≥ 2) in patients with at least one metabolic risk factor."
"The ELF test* is a non-invasive blood test that measures three direct markers of fibrosis: hyaluronic acid (HA), procollagen III amino-terminal peptide (PIIINP), and tissue inhibitor of matrix metalloproteinase 1 (TIMP-1). The ELF test, in conjunction with other laboratory and clinical findings, can be used to assess the risk of progression to cirrhosis and LREs in patients with chronic liver disease."
Often referred to as Fibroscan, is a non-invasive way of assessing liver fibrosis by measuring the 'hardness' or stiffness of the liver. It is a non-invasive procedure that can be done in a clinic.
Real-time shear wave elastography (RT-SWE), is another ultrasonographic technique for measuring liver stiffness and has been considered an alternative to Transient Elastography for the non-invasive measurement of liver fibrosis.
MRE is used to detect stiffening of the liver caused by fibrosis and inflammation in chronic liver disease., and provides quantitative maps of tissue stiffness over large regions of the liver.
Shear wave elastography is an important non-invasive ultrasound applied technique for assessment of liver stiffness and prediction of the presence of gastro-esophageal varices in cirrhotic patients.
Dr. Richard Sterling, the creator of the FIB-4 liver assessment diagnostic test in 2006 shares a lot about when and why he developed the test and how best to use it, to predict which patients might be more likely of having fibrosis and increased risk of advanced liver disease.