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Fatty Liver Alliance: Advancing Awareness and Advocacy for MASLD and MASH
Steatotic Liver Disease (MASLD/MASH)

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Steatotic Liver Disease (MASLD/MASH)
The statistics are clear—MASLD is on the rise, and without urgent intervention, its impact will only worsen. Addressing this crisis requires more than just awareness; it demands a fundamental shift in how we educate future physicians.
Nonalcoholic steatohepatitis (NASH), now classified under metabolic dysfunction-associated steatohepatitis (MASH), is a progressive liver disease that can lead to fibrosis, cirrhosis, and severe liver complications. The challenge in managing MASH has always been how to effectively monitor patient response to treatment without relying on invasive liver biopsies.
At the recent Desert Liver Conference, Dr. Mazen Noureddin provided valuable insights into non-invasive methods for tracking treatment response, discussing both clinical trial applications and real-world practice.
Summary of Dr. Naim Alkhouri’s Presentation on Non-Invasive Tests (NITs) for MASLD/MASH Screening in Clinical Practice from the Desert Liver Conference 2025.
Dr. Naim Alkhouri, along with Dr. Mazen Noureddin and Dr. Meena Bansal (summaries of their presentations to follow), discussed the clinical perspective on non-invasive tests (NITs) for identifying and managing MASLD/MASH patients, particularly in primary care and diabetes clinics.
Dr. Supriya Joshi emphasizes that MASLD and MASH are common yet often overlooked conditions affecting nearly 40% of the global population. She highlighted that early detection through simple tests like FIB-4 and FibroScan is crucial, as MASH can lead to liver fibrosis, cirrhosis, and even liver cancer if left untreated.
However, she provides hope by demonstrating that MASLD and MASH are preventable and reversible through lifestyle changes, weight management, and emerging pharmaceutical treatments.
If you’ve been diagnosed with Metabolic dysfunction-Associated Steatohepatitis (MASH), you may have felt frustrated by the lack of available treatment options in the past. But 2024 is a breakthrough year, and the future is looking brighter than ever!
In this final installment of the Liver Insights 2 series, we will walk you through the latest treatments, exciting new developments on the horizon, and most importantly, what you can do to take control of your liver health today.
If you’ve been diagnosed with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) or Metabolic Dysfunction-Associated Steatohepatitis (MASH), you might feel overwhelmed or unsure about what comes next. But here’s the truth: you are your own best advocate in the healthcare system.
In a recent conversation between Michael Betel, President of the Fatty Liver Alliance, and Dr. Supriya Joshi, a Hepatologist and patient advocate, we explored how patients can take control of their healthcare journey. Here are the key takeaways and practical steps to help you advocate for yourself effectively.
For many, the initial shock of diagnosis can lead to a whirlwind of emotions—fear, anxiety, confusion, and sometimes even guilt. Gina Villiotti-Madison, Executive Director of Liver Education Advocates, shared during our recent Liver Insights II series that it is normal to feel this way. She emphasized that while it is okay to sit with these feelings briefly, finding a path forward is crucial.
At the 2025 Primary Care MASLD and MASH Summit, Dr. Naim Alkhouri, Head of the Liver Transplant Program in Phoenix, delivered an urgent message to healthcare providers: “Just do something.”
The fight against MASH requires immediate action, and thanks to new drug approvals, we now have effective pharmacological tools to complement lifestyle interventions.
Diet is the foundation of MASLD and MASH management. Poor dietary habits contribute significantly to liver fat accumulation, inflammation, fibrosis, and even liver cancer. While many believe that weight loss alone is the key, diet quality is just as important.
"If you don’t take care of your liver, it won’t take care of you." – Prof. Shira Zelber-Sagi
The Fatty Liver Alliance a Canada-based advocacy group, is calling for supporters to sign a petition asking Madrigal Pharmaceuticals to apply to Canadian regulators for approval of Rezdiffra (resmetirom), the company’s oral therapy for metabolic dysfunction-associated steatohepatitis (MASH).
https://liverdiseasenews.com/news/nonprofits-petition-aims-expedite-canadian-access-rezdiffra/
Today, we're taking a crucial step forward in advocating for Canadians diagnosed with MASH (Metabolic dysfunction-Associated Steatohepatitis).
We've launched a petition asking Madrigal Pharmaceuticals to apply to Health Canada, so that Canadians can have access to Rezdiffra—a vital treatment for MASH.
Your support is essential! Please take a moment to sign our petition and share this with your network. Together, we can make a difference!
🔗 Sign the Petition Here: https://globalliver.salsalabs.org/petitionrezdiffracanada
🔗 Read Our Media Release: Urgent Call to Action: Canadians Deserve Equal Access to Life-Saving Liver Treatment--Sign the Petition Now!
Thank you for standing with us in this important cause.
Our amazing team of full and part-time volunteers are committed to helping others. We take our convictions and turn them into action. Think you would be a good fit? Get in touch for more information!
Our nonprofit charity was created to build a supportive community. Canada’s population is about 38.8M with an estimated 15.5M who may have Metabolic Dysfunction Associated Liver Disease (MASLD) (formerly NAFLD). Of those, an estimated 20% - 25% will progress to cirrhosis and suffer with Metabolic-dysfunction Associated Steatohepatitis (MASH) (formerly NASH).
We raise awareness about the risks, causes and complications of fatty liver disease and help those already diagnosed with MASLD or MASH by advocating for access to approved treatments and care.
Your support and contributions will enable our Registered Charity to meet our goals and your generous donations will fund our mission and purpose. Charity #79690 4704 RR0001
We will issue a tax receipt for donations of $18.00 or greater.
**Best option for us, is e-transfer to donations@fattyliver.ca
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